KRT79

KRT79
Identifiers
AliasesKRT79, K6L, KRT6L, keratin 79
External IDsOMIM: 611160; MGI: 2385030; HomoloGene: 89169; GeneCards: KRT79; OMA:KRT79 - orthologs
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for KRT79
Genomic location for KRT79
Band12q13.13Start52,821,408 bp[1]
End52,834,311 bp[1]
Gene location (Mouse)
Chromosome 15 (mouse)
Chr.Chromosome 15 (mouse)[2]
Chromosome 15 (mouse)
Genomic location for KRT79
Genomic location for KRT79
Band15|15 F2Start101,837,767 bp[2]
End101,848,759 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • skin of thigh

  • vulva

  • skin of abdomen

  • nipple

  • subcutaneous adipose tissue

  • mammary gland

  • lactiferous gland

  • upper lobe of left lung

  • right lung

  • islet of Langerhans
Top expressed in
  • lip

  • skin of external ear

  • skin of back

  • right lung lobe

  • mucous cell of stomach

  • skin of abdomen

  • sexually immature organism

  • epidermis

  • conjunctival fornix

  • embryo
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • enzyme binding
  • protein binding
  • structural molecule activity
Cellular component
  • keratin filament
  • extracellular exosome
  • intermediate filament
  • cytosol
Biological process
  • keratinization
  • cornification
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

338785

223917

Ensembl

ENSG00000185640

ENSMUSG00000061397

UniProt

Q5XKE5

Q8VED5

RefSeq (mRNA)

NM_175834

NM_146063

RefSeq (protein)

NP_787028

NP_666175

Location (UCSC)Chr 12: 52.82 – 52.83 MbChr 15: 101.84 – 101.85 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Keratin 79 also known as KRT79 is a protein which humans is encoded by the KRT79 gene.[5][6]

Function

Keratins, such as KRT79, are filament proteins that make up one of the major structural fibers of epithelial cells[7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000185640 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000061397 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Hesse M, Magin TM, Weber K (July 2001). "Genes for intermediate filament proteins and the draft sequence of the human genome: novel keratin genes and a surprisingly high number of pseudogenes related to keratin genes 8 and 18". J. Cell Sci. 114 (Pt 14): 2569–75. doi:10.1242/jcs.114.14.2569. PMID 11683385.
  6. ^ "Entrez Gene: KRT79 keratin 79".
  7. ^ Rogers MA, Edler L, Winter H, Langbein L, Beckmann I, Schweizer J (March 2005). "Characterization of new members of the human type II keratin gene family and a general evaluation of the keratin gene domain on chromosome 12q13.13". J. Invest. Dermatol. 124 (3): 536–44. doi:10.1111/j.0022-202X.2004.23530.x. PMID 15737194.

Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Sowa ME, Bennett EJ, Gygi SP, Harper JW (2009). "Defining the human deubiquitinating enzyme interaction landscape". Cell. 138 (2): 389–403. doi:10.1016/j.cell.2009.04.042. PMC 2716422. PMID 19615732.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


  • v
  • t
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Human
Microfilaments
and ABPs
Myofilament
Actins
Myosins
Other
Other
Intermediate
filaments
Type 1/2
(Keratin,
Cytokeratin)
Epithelial keratins
(soft alpha-keratins)
Hair keratins
(hard alpha-keratins)
Ungrouped alpha
Not alpha
Type 3
Type 4
Type 5
Microtubules
and MAPs
Tubulins
MAPs
Kinesins
Dyneins
Microtubule organising proteins
Microtubule severing proteins
Other
Catenins
Membrane
Other
Nonhuman
See also: cytoskeletal defects


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