T-cell growth factor

T-cell growth factors acronym: TCGF(s) are signaling molecules collectively called growth factors which stimulate the production and development of T-cells. A number of them have been discovered, among them many members of the interleukin family. The thymus is one organ which releases TCGFs. TCGFs have been able to induce T-cell production outside the body for injection.

List of TCGFs

  • IL-2[1][full citation needed]
  • IL-7[2][full citation needed]
  • IL-9[3]
  • IL-15[4]
This list is incomplete; you can help by adding missing items. (August 2015)

References

  1. ^ Oppenheim, Joost J. (August 1, 2007). "IL-2: More Than a T Cell Growth Factor". The Journal of Immunology. 179 (3): 1413–1414. doi:10.4049/jimmunol.179.3.1413. PMID 17641004 – via www.jimmunol.org.
  2. ^ Chazen, G D; Pereira, G M; LeGros, G; Gillis, S; Shevach, E M (1989). "Interleukin 7 is a T-cell growth factor". Proceedings of the National Academy of Sciences of the United States of America. 86 (15): 5923–5927. Bibcode:1989PNAS...86.5923C. doi:10.1073/pnas.86.15.5923. ISSN 0027-8424. PMC 297743. PMID 2788279.
  3. ^ "Jena Bioscience - Products & Ordering - Recombinant Proteins - Cytokines and Growth Factors - T-Cell Growth Factors". www.jenabioscience.com. Archived from the original on 2007-11-14.
  4. ^ Steel, JC; Waldmann, TA; Morris, JC (January 2012). "Interleukin-15 biology and its therapeutic implications in cancer". Trends Pharmacol. Sci. 33 (1): 35–41. doi:10.1016/j.tips.2011.09.004. PMC 3327885. PMID 22032984.
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