FGF11

fibroblast growth factor 11
Identifiers
SymbolFGF11
Alt. symbolsFHF3, FLJ16061, MGC45269, MGC102953
NCBI gene2256
HGNC3667
OMIM601514
RefSeqNM_004112
UniProtQ92914
Other data
LocusChr. 17 p13.1
Search for
StructuresSwiss-model
DomainsInterPro

Fibroblast growth factor 11 also known as FGF11 is a human gene.[1][2]

The protein encoded by this gene is a member of the intracellular fibroblast growth factor family.[3] The function of FGF11 is unknown.

References

  1. ^ Smallwood PM, Munoz-Sanjuan I, Tong P, Macke JP, Hendry SH, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J (September 1996). "Fibroblast growth factor (FGF) homologous factors: new members of the FGF family implicated in nervous system development". Proc. Natl. Acad. Sci. U.S.A. 93 (18): 9850–7. Bibcode:1996PNAS...93.9850S. doi:10.1073/pnas.93.18.9850. PMC 38518. PMID 8790420.
  2. ^ Verdier AS, Mattei MG, Lovec H, Hartung H, Goldfarb M, Birnbaum D, Coulier F (February 1997). "Chromosomal mapping of two novel human FGF genes, FGF11 and FGF12". Genomics. 40 (1): 151–4. doi:10.1006/geno.1996.4492. PMID 9070933.
  3. ^ Itoh N, Ornitz DM (January 2008). "Functional evolutionary history of the mouse Fgf gene family". Dev. Dyn. 237 (1): 18–27. doi:10.1002/dvdy.21388. PMID 18058912. S2CID 5684356.
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Angiopoietin
  • Kinase inhibitors: Altiratinib
  • CE-245677
  • Rebastinib
CNTF
EGF (ErbB)
EGF
(ErbB1/HER1)
ErbB2/HER2
  • Agonists: Unknown/none
ErbB3/HER3
ErbB4/HER4
FGF
FGFR1
FGFR2
  • Antibodies: Aprutumab
  • Aprutumab ixadotin
FGFR3
FGFR4
Unsorted
HGF (c-Met)
IGF
IGF-1
  • Kinase inhibitors: BMS-754807
  • Linsitinib
  • NVP-ADW742
  • NVP-AEW541
  • OSl-906
IGF-2
  • Antibodies: Dusigitumab
  • Xentuzumab (against IGF-1 and IGF-2)
Others
  • Cleavage products/derivatives with unknown target: Glypromate (GPE, (1-3)IGF-1)
  • Trofinetide
LNGF (p75NTR)
  • Aptamers: Against NGF: RBM-004
  • Decoy receptors: LEVI-04 (p75NTR-Fc)
PDGF
RET (GFL)
GFRα1
GFRα2
GFRα3
GFRα4
Unsorted
  • Kinase inhibitors: Agerafenib
SCF (c-Kit)
TGFβ
  • See here instead.
Trk
TrkA
  • Negative allosteric modulators: VM-902A
  • Aptamers: Against NGF: RBM-004
  • Decoy receptors: ReN-1820 (TrkAd5)
TrkB
TrkC
VEGF
Others


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