Tixocortol

Medication
  • A07EA05 (WHO) R01AD07 (WHO)
Identifiers
  • (11β)-11,17-Dihydroxy-21-mercaptopregn-4-ene-3,20-dione
CAS Number
  • 61951-99-3 ☒N
PubChem CID
  • 162955
ChemSpider
  • 143053 checkY
UNII
  • ZX3KEK657Z
KEGG
  • D08610 checkY
CompTox Dashboard (EPA)
  • DTXSID30895062 Edit this at Wikidata
ECHA InfoCard100.128.190 Edit this at WikidataChemical and physical dataFormulaC21H30O4SMolar mass378.53 g·mol−13D model (JSmol)
  • Interactive image
  • O=C4\C=C2/[C@]([C@H]1[C@@H](O)C[C@@]3([C@@](O)(C(=O)CS)CC[C@H]3[C@@H]1CC2)C)(C)CC4
InChI
  • InChI=1S/C21H30O4S/c1-19-7-5-13(22)9-12(19)3-4-14-15-6-8-21(25,17(24)11-26)20(15,2)10-16(23)18(14)19/h9,14-16,18,23,25-26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1 checkY
  • Key:YWDBSCORAARPPF-VWUMJDOOSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Tixocortol is a corticosteroid used as an intestinal anti-inflammatory[1] and decongestant.

See also

  • Tixocortol pivalate

References

  1. ^ Larochelle P, Du Souich P, Bolte E, Lelorier J, Goyer R (March 1983). "Tixocortol pivalate, a corticosteroid with no systemic glucocorticoid effect after oral, intrarectal, and intranasal application". Clinical Pharmacology and Therapeutics. 33 (3): 343–50. doi:10.1038/clpt.1983.43. PMID 6402333. S2CID 29876079.
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Glucocorticoids and antiglucocorticoids (D07, H02)
Glucocorticoids
Natural
Synthetic
AntiglucocorticoidsSynthesis modifiers
See also
Glucocorticoid receptor modulators
Mineralocorticoids and antimineralocorticoids
List of corticosteroids
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Rehydration
Intestinal anti-infectives
Intestinal adsorbents
Antipropulsives (opioids)
Intestinal anti-inflammatory agents
Antidiarrheal micro-organisms
Other antidiarrheals
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Decongestants and other nasal preparations (R01)
Topical
Sympathomimetics, plain
Antiallergic agents,
excluding corticosteroids
Corticosteroids
Other nasal preparations
Combination products
Systemic use:
Sympathomimetics
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GRTooltip Glucocorticoid receptor
Agonists
  • Nonsteroidal glucocorticoids: AZD-5423
  • GSK-9027
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others
  • Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)
See also
Receptor/signaling modulators
Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids
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