Uracil fosforiboziltransferaza

Uracil fosforiboziltransferaza
Identifikatori
EC broj 2.4.2.9
CAS broj 9030-24-4
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB RCSB PDB PDBe PDBj PDBsum
Pretraga
PMC articles
PubMed articles
NCBI Protein search

Uracil fosforiboziltransferaza (EC 2.4.2.9, UMP pirofosforilaza, UPRTaze, UMP:pirofosfat fosforiboziltransferaza, uridin 5'-fosfat pirofosforilaza, uridin monofosfatna pirofosforilaza, uridilatna pirofosforilaza, uridilinska pirofosforilaza) je enzim sa sistematskim imenom UMP:difosfat fosfo-alfa-D-riboziltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju

UMP + difosfat ⇌ {\displaystyle \rightleftharpoons } uracil + 5-fosfo-alfa-D-riboza 1-difosfat

Reference

  1. ↑ Crawford, I., Kornberg, A. and Simms, E.S. (1967). „Conversion of uracil and orotate to uridine 5′-phosphate by enzymes in lactobacilli”. J. Biol. Chem. 226: 1093-1101. PMID 13438895. 
  2. ↑ Flaks, J.G. (1963). „Nucleotide synthesis from 5-phosphoribosylpyrophosphate”. Methods Enzymol. 6: 136-158. 

Literatura

  • Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
  • Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
  • Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Spoljašnje veze

  • MeSH Uracil+phosphoribosyltransferase
  • p
  • r
  • u
TemeTipovi
EC1 Oksidoreduktaze/spisak  • EC2 Transferaze/spisak  • EC3 Hidrolaze/spisak  • EC4 Lijaze/spisak  • EC5 Izomeraze/spisak  • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6