ZNF133

Protein-coding gene in the species Homo sapiens
ZNF133
Identifiers
AliasesZNF133, ZNF150, pHZ-13, pHZ-66, zinc finger protein 133
External IDsOMIM: 604075; HomoloGene: 48184; GeneCards: ZNF133; OMA:ZNF133 - orthologs
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for ZNF133
Genomic location for ZNF133
Band20p11.23Start18,288,283 bp[1]
End18,316,996 bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • cerebellar hemisphere

  • right hemisphere of cerebellum

  • parotid gland

  • anterior pituitary

  • pancreatic ductal cell

  • apex of heart

  • right lobe of thyroid gland

  • left lobe of thyroid gland

  • right frontal lobe

  • ganglionic eminence
    n/a
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • DNA-binding transcription factor activity
  • DNA binding
  • protein binding
  • metal ion binding
  • nucleic acid binding
  • DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component
  • intracellular anatomical structure
  • nucleus
Biological process
  • regulation of transcription, DNA-templated
  • transcription, DNA-templated
  • regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

7692

n/a

Ensembl

ENSG00000125846

n/a

UniProt

P52736
Q5JXW1

n/a

RefSeq (mRNA)
NM_001083330
NM_001282995
NM_001282996
NM_001282997
NM_001282998

NM_001282999
NM_001283000
NM_001283001
NM_001283002
NM_001283003
NM_001283004
NM_001283005
NM_001283006
NM_001283007
NM_001283008
NM_003434
NM_001352450
NM_001352451
NM_001352452
NM_001352453
NM_001352454
NM_001352455
NM_001352456
NM_001352457
NM_001352458
NM_001352459
NM_001352460
NM_001352461
NM_001352462
NM_001352463
NM_001352464

n/a

RefSeq (protein)
NP_001076799
NP_001269924
NP_001269925
NP_001269926
NP_001269927

NP_001269928
NP_001269929
NP_001269930
NP_001269931
NP_001269932
NP_001269933
NP_001269934
NP_001269935
NP_001269936
NP_001269937
NP_003425
NP_001339379
NP_001339380
NP_001339381
NP_001339382
NP_001339383
NP_001339384
NP_001339385
NP_001339386
NP_001339387
NP_001339388
NP_001339389
NP_001339390
NP_001339391
NP_001339392
NP_001339393

n/a

Location (UCSC)Chr 20: 18.29 – 18.32 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Zinc finger protein 133 is a protein that in humans is encoded by the ZNF133 gene.[3][4][5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000125846 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Tommerup N, Vissing H (Nov 1995). "Isolation and fine mapping of 16 novel human zinc finger-encoding cDNAs identify putative candidate genes for developmental and malignant disorders". Genomics. 27 (2): 259–64. doi:10.1006/geno.1995.1040. PMID 7557990.
  4. ^ Vissing H, Meyer WK, Aagaard L, Tommerup N, Thiesen HJ (Sep 1995). "Repression of transcriptional activity by heterologous KRAB domains present in zinc finger proteins". FEBS Lett. 369 (2–3): 153–7. doi:10.1016/0014-5793(95)00728-R. PMID 7649249. S2CID 8254920.
  5. ^ "Entrez Gene: ZNF133 zinc finger protein 133".

Further reading

  • Lee SJ, Lee JR, Hahn HS, et al. (2007). "PIAS1 interacts with the KRAB zinc finger protein, ZNF133, via zinc finger motifs and regulates its transcriptional activity". Exp. Mol. Med. 39 (4): 450–7. doi:10.1038/emm.2007.49. PMID 17934332.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ehringer MA, Thompson J, Conroy O, et al. (2004). "Human alcoholism studies of genes identified through mouse quantitative trait locus analysis". Addict Biol. 7 (4): 365–71. doi:10.1080/1355621021000005496. PMID 14578011. S2CID 25447012.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
  • Moosmann P, Georgiev O, Thiesen HJ, et al. (1998). "Silencing of RNA polymerases II and III-dependent transcription by the KRAB protein domain of KOX1, a Krüppel-type zinc finger factor". Biol. Chem. 378 (7): 669–77. doi:10.1515/bchm.1997.378.7.669. PMID 9278146.


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