UCKL1

Protein-coding gene in the species Homo sapiens
UCKL1
Identifiers
AliasesUCKL1, UCK1-LIKE, UCK1L, URKL1, uridine-cytidine kinase 1 like 1
External IDsOMIM: 610866; MGI: 1915806; HomoloGene: 101414; GeneCards: UCKL1; OMA:UCKL1 - orthologs
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for UCKL1
Genomic location for UCKL1
Band20q13.33Start63,939,829 bp[1]
End63,956,416 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for UCKL1
Genomic location for UCKL1
Band2|2 H4Start181,210,942 bp[2]
End181,226,685 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right uterine tube

  • canal of the cervix

  • right lobe of thyroid gland

  • left lobe of thyroid gland

  • tibial nerve

  • left uterine tube

  • transverse colon

  • anterior pituitary

  • minor salivary glands

  • gastric mucosa
Top expressed in
  • superior frontal gyrus

  • proximal tubule

  • thymus

  • lip

  • interventricular septum

  • cerebellar cortex

  • duodenum

  • skeletal muscle tissue

  • esophagus

  • olfactory epithelium
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • transferase activity
  • nucleotide binding
  • protein binding
  • ATP binding
  • kinase activity
  • uridine kinase activity
Cellular component
  • cytoplasm
  • nucleus
  • cytosol
Biological process
  • metabolism
  • viral process
  • pyrimidine nucleobase metabolic process
  • UMP salvage
  • CTP salvage
  • phosphorylation
  • nucleoside metabolic process
  • pyrimidine nucleoside salvage
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

54963

68556

Ensembl

ENSG00000198276

ENSMUSG00000089917

UniProt

Q9NWZ5

Q91YL3

RefSeq (mRNA)
NM_001193379
NM_017859
NM_001353475
NM_001353476
NM_001353477

NM_001353478
NM_001353479
NM_001353480
NM_001353481
NM_001353482

NM_026765
NM_001379005

RefSeq (protein)
NP_001180308
NP_060329
NP_001340404
NP_001340405
NP_001340406

NP_001340407
NP_001340408
NP_001340409
NP_001340410
NP_001340411

NP_081041
NP_001365934

Location (UCSC)Chr 20: 63.94 – 63.96 MbChr 2: 181.21 – 181.23 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Uridine-cytidine kinase-like 1 is an enzyme that in humans is encoded by the UCKL1 gene.[5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000198276 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000089917 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: UCKL1 uridine-cytidine kinase 1-like 1".

Further reading

  • Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Kashuba E, Kashuba V, Sandalova T, et al. (2002). "Epstein-Barr virus encoded nuclear protein EBNA-3 binds a novel human uridine kinase/uracil phosphoribosyltransferase". BMC Cell Biol. 3: 23. doi:10.1186/1471-2121-3-23. PMC 126255. PMID 12199906.
  • Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi:10.1038/414865a. PMID 11780052.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.


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