Sodium orthovanadate

Sodium orthovanadate
Names
IUPAC name
Sodium vanadate(V)
Other names
Sodium vanadium oxide
Identifiers
CAS Number
  • 13721-39-6 (anhydrous) checkY
3D model (JSmol)
  • Interactive image
ChEBI
  • CHEBI:35607
ChEMBL
  • ChEMBL179166 ☒N
ECHA InfoCard 100.033.883 Edit this at Wikidata
PubChem CID
  • 61671
RTECS number
  • YW1120000
UNII
  • 7845MV6C8V checkY
CompTox Dashboard (EPA)
  • DTXSID2037269 Edit this at Wikidata
InChI
  • InChI=1S/3Na.4O.V/q3*+1;;3*-1;
  • [O-] [V](=O)([O-])[O-].[Na+].[Na+].[Na+]
Properties
Chemical formula
 Na3VO4
Molar mass 183.908 g/mol
Appearance white powder
Density 2.16 g/cm3, solid
Melting point 858 °C (1,576 °F; 1,131 K)
Solubility in water
 22.17 g/100 mL
Solubility insoluble in ethanol
Structure
Crystal structure
 cubic
Thermochemistry
Heat capacity (C)
 164.8 J/mol K
Std molar
entropy (S⦵298)
 190 J/mol K
Std enthalpy of
formation (ΔfH⦵298)
 −1757 kJ/mol
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Harmful.
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 3: Short exposure could cause serious temporary or residual injury. E.g. chlorine gasFlammability 0: Will not burn. E.g. waterInstability 0: Normally stable, even under fire exposure conditions, and is not reactive with water. E.g. liquid nitrogenSpecial hazards (white): no code
3
0
0
Flash point Non-flammable
Lethal dose or concentration (LD, LC):
330 mg/kg (oral, rat)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
Chemical compound

Sodium orthovanadate is the inorganic compound with the chemical formula Na3V O4. It forms a dihydrate Na3VO4·2H2O. Sodium orthovanadate is a salt of the VO3−4 oxyanion. It is a colorless, water-soluble solid.[2]

Synthesis and structure

Sodium orthovanadate is produced by dissolving vanadium(V) oxide in a solution of sodium hydroxide:

V2O5 + 6 NaOH → 2 Na3VO4 + 3 H2O

The salt features tetrahedral VO3−4 anion centers linked to octahedral Na+ cation sites.[3]

Condensation equilibria

Like many oxometalates, orthovanadate is subject to a number of reactions, which have been analyzed by 51V NMR studies. At high pH, VO3−4 ions exist in equilibrium with HVO2−4.[4] At lower pH's, condensation ensues to give various polyoxovanadates. Ultimately, decavanadate is formed.[5]

Biochemistry

Vanadates exhibit a variety of biological activities, in part because they serve as structural mimics of phosphates.[6][7] It acts as a competitive inhibitor of ATPases, alkaline and acid phosphatases, and protein-phosphotyrosine phosphatases,[8] and its inhibitory effects can be reversed by dilution or the addition of ethylenediaminetetraacetic acid (EDTA).[9]

Orthovanadate is activated by boiling and adjusting pH to ~10; this depolymerizes decavanadate into the active inhibitor, monovanadate.[8]

References

  1. ^ "Archived copy". Archived from the original on 2016-03-04. Retrieved 2017-09-28.{{cite web}}: CS1 maint: archived copy as title (link)
  2. ^ Greenwood, Norman N.; Earnshaw, Alan (1997). Chemistry of the Elements (2nd ed.). Butterworth-Heinemann. ISBN 978-0-08-037941-8.
  3. ^ Kato, K.; Takayama-Muromachi, E. (1987). "Die Struktur des Trinatriumvanadattrihydrats" [The structure of trisodium vanadate trihydrate] (PDF). Acta Crystallogr. C43 (6): 1030–1032. Bibcode:1987AcCrC..43.1030K. doi:10.1107/S0108270187093120.
  4. ^ Rehder, D.; Polenova, T.; Bühl, M. (2007). Vanadium-51 NMR. Annual Reports on NMR Spectroscopy. Vol. 62. pp. 49–114. doi:10.1016/S0066-4103(07)62002-X. ISBN 9780123739193.
  5. ^ Klemperer, W. G.; Yaghi, O. (1983). "Tetrabutylammonium Trihydrogen Decavanadate(V)". Inorg. Synth. 27: 83. doi:10.1002/9780470132586.ch15.
  6. ^ Korbecki, Jan; Baranowska-Bosiacka, Irena; Gutowska, Izabela; Chlubek, Dariusz (2012). "Biochemical and medical importance of vanadium compounds" (PDF). Acta Biochim. Pol. 59 (2): 195–200. doi:10.18388/abp.2012_2138. PMID 22693688.
  7. ^ Crans, D. C.; Chatterjee, P. B. (2013). "Vanadium biochemistry". In Reedijk, Jan; Poeppelmeier, Kenneth (eds.). Comprehensive Inorganic Chemistry II: From Elements to Applications. Comprehensive Inorganic Chemistry II. Vol. 3. pp. 323–342. doi:10.1016/B978-0-08-097774-4.00324-7. ISBN 978-0-08-097774-4.
  8. ^ a b "Sodium orthovanadate" (PDF). Sigma-Aldrich. Retrieved September 7, 2018.
  9. ^ Biolabs, New England. "Sodium Orthovanadate (Vanadate) | NEB". www.neb.com. Retrieved 2018-09-07.

See also

  • v
  • t
  • e
Inorganic
Halides
Chalcogenides
Pnictogenides
  • Na3N
  • NaN3
  • NaNH2
  • Na3P
  • Na3As
Oxyhalides
  • NaClO
  • NaClO2
  • NaClO3
  • NaClO4
  • NaBrO
  • NaBrO2
  • NaBrO3
  • NaBrO4
  • NaIO3
  • NaIO4
Oxychalcogenides
  • Na2SO3
  • Na2SO4
  • NaHSO3
  • NaHSO4
  • Na2S2O3
  • Na2S2O4
  • Na2S2O5
  • Na2S2O6
  • Na2S2O7
  • Na2S2O8
  • Na2SeO3
  • Na2SeO4
  • NaHSeO3
  • Na2TeO3
Oxypnictogenides
  • NaNO2
  • NaNO3
  • Na2N2O2
  • NaH2PO4
  • NaPO2H2
  • Na2HPO3
  • Na2PO3F
  • Na3PS2O2
  • Na3PO4
  • Na5P3O10
  • Na4P2O7
  • Na2H2P2O7
  • Na3AsO3
  • Na3AsO4
  • Na2HAsO4
  • NaH2AsO4
  • NaSbO3
Others
  • NaAlH4
  • NaAlO2
  • Na3AlF6
  • NaAl(SO4)2
  • NaAuCl4
  • Na2TiF6
  • NaBH4
  • NaBH3(CN)
  • NaBO2
  • Na2B4O7
  • Na2B2O9
  • Na2B8O13
  • NaBiO3
  • NaCN
  • NaCNO
  • NaCoO2
  • NaH
  • NaHCO3
  • Na4XeO6
  • NaHXeO4
  • NaMnO4
  • NaOCN
  • NaReO4
  • NaSCN
  • NaTcO3
  • NaTcO4
  • NaVO3
  • Na2CO3
  • Na2C2O4
  • Na2C3S5
  • Na2CrO4
  • Na2Cr2O7
  • Na2Cr3O10
  • Na2GeO3
  • Na2He
  • Na2[Fe(CO)4]
  • Na2MnO4
  • Na2MoO4
  • Na3IrCl6
  • Na2PtCl6
  • Na2O(UO3)2
  • Na2S4O6
  • Na2SiO3
  • Na2TiO3
  • Na2U2O7
  • Na2WO4
  • Na2Zn(OH)4
  • Na3VO4
  • Na6V10O28
  • Na4Fe(CN)6
  • Na3Fe(CN)6
  • Na3Fe(C2O4)3
  • Na4SiO4
  • Na2SiF6
  • Na3[Co(NO2)6]
  • NaNSi6
  • Na2PdCl4
Organic
  • CH3ONa
  • C2H5ONa
  • HCOONa
  • C2H5COONa
  • C3H7COONa
  • Na2C4H4O6
  • C4H5NaO6
  • NaCH3COO
  • NaC6H5CO2
  • NaC6H4(OH)CO2
  • NaC12H23O2
  • NaC10H8
  • Na2[Fe[CN5]NO]
  • C6H16AlNaO4
  • NaC6H7O6
  • C5H8NO4Na
  • C6H5Na
  • C4H9Na
  • NaC5H5
  • C15H31COONa
  • C17H33COONa
  • C18H35O2Na
  • C164H256O68S2Na2