NOL9

Protein-coding gene in the species Homo sapiens
NOL9
Identifiers
AliasesNOL9, Grc3, NET6, nucleolar protein 9
External IDsMGI: 1921285; HomoloGene: 32589; GeneCards: NOL9; OMA:NOL9 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for NOL9
Genomic location for NOL9
Band1p36.31Start6,521,347 bp[1]
End6,554,513 bp[1]
Gene location (Mouse)
Chromosome 4 (mouse)
Chr.Chromosome 4 (mouse)[2]
Chromosome 4 (mouse)
Genomic location for NOL9
Genomic location for NOL9
Band4|4 E2Start152,123,778 bp[2]
End152,145,951 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • tibialis anterior muscle

  • internal globus pallidus

  • nipple

  • Skeletal muscle tissue of rectus abdominis

  • deltoid muscle

  • biceps brachii

  • periodontal fiber

  • quadriceps femoris muscle

  • Brodmann area 46

  • vastus lateralis muscle
Top expressed in
  • lumbar subsegment of spinal cord

  • tail of embryo

  • epiblast

  • zygote

  • yolk sac

  • genital tubercle

  • primitive streak

  • secondary oocyte

  • hand

  • morula
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • transferase activity
  • nucleotide binding
  • polynucleotide 5'-hydroxyl-kinase activity
  • protein binding
  • ATP binding
  • RNA binding
  • kinase activity
Cellular component
  • membrane
  • nucleus
  • nucleoplasm
  • nucleolus
  • intermediate filament cytoskeleton
Biological process
  • cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • maturation of 5.8S rRNA
  • phosphorylation
  • rRNA processing
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

79707

74035

Ensembl

ENSG00000162408

ENSMUSG00000028948

UniProt

Q5SY16

Q3TZX8

RefSeq (mRNA)

NM_024654

NM_001159599
NM_028727
NM_001378856

RefSeq (protein)

NP_078930

NP_001153071
NP_083003
NP_001365785

Location (UCSC)Chr 1: 6.52 – 6.55 MbChr 4: 152.12 – 152.15 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Nucleolar protein 9 is a protein that in humans is encoded by the NOL9 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000162408 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028948 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Strausberg RL, Feingold EA, Grouse LH, et al. (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  6. ^ "Entrez Gene: NOL9 nucleolar protein 9".

Further reading

  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Scherl A, Couté Y, Déon C, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
  • Wistow G, Bernstein SL, Wyatt MK, et al. (2002). "Expressed sequence tag analysis of human RPE/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants". Mol. Vis. 8: 205–20. PMID 12107410.
  • Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.


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