Metildigoxin

Chemical compound
  • C
ATC code
  • C01AA08 (WHO)
Identifiers
  • (3β,5β,12β)-3-{[2,6-dideoxy-4-O-methyl-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl]oxy}-12,14-dihydroxycard-20(22)-enolide
CAS Number
  • 30685-43-9
PubChem CID
  • 443946
ChemSpider
  • 392000 checkY
UNII
  • I7GG1YUC5V
CompTox Dashboard (EPA)
  • DTXSID0023294 Edit this at Wikidata
ECHA InfoCard100.045.705 Edit this at WikidataChemical and physical dataFormulaC42H66O14Molar mass794.976 g·mol−13D model (JSmol)
  • Interactive image
  • O=C\1OC/C(=C/1)[C@H]2CC[C@@]8(O)[C@]2(C)[C@H](O)C[C@H]7[C@H]8CC[C@H]6[C@]7(C)CC[C@H](O[C@@H]5O[C@H](C)[C@@H](O[C@@H]4O[C@@H]([C@@H](O[C@@H]3O[C@@H]([C@@H](OC)[C@@H](O)C3)C)[C@@H](O)C4)C)[C@@H](O)C5)C6
InChI
  • InChI=1S/C42H66O14/c1-20-37(49-6)29(43)16-35(51-20)55-39-22(3)53-36(18-31(39)45)56-38-21(2)52-34(17-30(38)44)54-25-9-11-40(4)24(14-25)7-8-27-28(40)15-32(46)41(5)26(10-12-42(27,41)48)23-13-33(47)50-19-23/h13,20-22,24-32,34-39,43-46,48H,7-12,14-19H2,1-6H3/t20-,21-,22-,24-,25+,26-,27-,28+,29+,30+,31+,32-,34+,35+,36+,37-,38-,39-,40+,41+,42+/m1/s1 checkY
  • Key:IYJMSDVSVHDVGT-PEQKVOOWSA-N checkY
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Metildigoxin (INN, or medigoxin BAN, or methyldigoxin) is a cardiac glycoside,[1] a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). The substance is closely related to digoxin; it differs from the latter only by an O-methyl group on the terminal monosaccharide.

References

  1. ^ Hayward R, Greenwood H, Stephens J, Hamer J (January 1983). "Relationship between myocardial uptake and actions in heart failure of methyldigoxin". British Journal of Clinical Pharmacology. 15 (1): 41–8. doi:10.1111/j.1365-2125.1983.tb01461.x. PMC 1427830. PMID 6849743.
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