Iscotrizinol

Iscotrizinol
Names

Preferred IUPAC name Bis(2-ethylhexyl) 4,4′-[(6-{[4-(tert-butylcarbamoyl)phenyl]amino}-1,3,5-triazine-2,4-diyl)bis(azanediyl)]dibenzoate
Other names Diethylhexyl butamido triazone (INCI), Uvasorb HEB (trade name)
Identifiers
CAS Number	154702-15-5^Y
3D model (JSmol)	Interactive image
ChemSpider	7986571^Y
ECHA InfoCard	100.102.002
KEGG	D09714^N
PubChem CID	9810816
UNII	2UTZ0QC864^Y
CompTox Dashboard (EPA)	DTXSID40870027
InChI InChI=1S/C44H59N7O5/c1-8-12-14-30(10-3)28-55-39(53)33-18-24-36(25-19-33)46-42-48-41(45-35-22-16-32(17-23-35)38(52)51-44(5,6)7)49-43(50-42)47-37-26-20-34(21-27-37)40(54)56-29-31(11-4)15-13-9-2/h16-27,30-31H,8-15,28-29H2,1-7H3,(H,51,52)(H3,45,46,47,48,49,50)^Y Key: OSCJHTSDLYVCQC-UHFFFAOYSA-N^Y InChI=1/C44H59N7O5/c1-8-12-14-30(10-3)28-55-39(53)33-18-24-36(25-19-33)46-42-48-41(45-35-22-16-32(17-23-35)38(52)51-44(5,6)7)49-43(50-42)47-37-26-20-34(21-27-37)40(54)56-29-31(11-4)15-13-9-2/h16-27,30-31H,8-15,28-29H2,1-7H3,(H,51,52)(H3,45,46,47,48,49,50)/f/h45-47,51H InChI=1/C44H59N7O5/c1-8-12-14-30(10-3)28-55-39(53)33-18-24-36(25-19-33)46-42-48-41(45-35-22-16-32(17-23-35)38(52)51-44(5,6)7)49-43(50-42)47-37-26-20-34(21-27-37)40(54)56-29-31(11-4)15-13-9-2/h16-27,30-31H,8-15,28-29H2,1-7H3,(H,51,52)(H3,45,46,47,48,49,50) Key: OSCJHTSDLYVCQC-UHFFFAOYAP
SMILES O=C(OCC(CC)CCCC)c1ccc(cc1)Nc2nc(nc(n2)Nc3ccc(C(=O)OCC(CC)CCCC)cc3)Nc4ccc(C(=O)NC(C)(C)C)cc4
Properties
Chemical formula	C₄₄H₅₉N₇O₅
Molar mass	765.981
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is ^YN ?) Infobox references

Chemical compound

Iscotrizinol (USAN,^[1] INCI diethylhexyl butamido triazone) is an organic compound used in sunscreens to absorb UVB and some UVA radiation ^[2] with a peak protection at 310 nm.^[3] It is one of the most photostable chemical sunscreens known today with 25 hours required to lose 10% of its SPF protection ability.^[4] It is marketed as Uvasorb HEB by 3V Sigma.

References

^ Statement on a nonproprietary name adopted by the USAN Council
^ incidecoder.com: Diethylhexyl Butamido Triazone
^ Couteau C, Pommier M, Paparis E, Coiffard LJ (June 2007). "Study of the efficacy of 18 sun filters authorized in European Union tested in vitro". Pharmazie. 62 (6): 449–452. doi:10.1691/ph.2007.6.6247. PMID 17663193.
^ Couteau C, Faure A, Fortin J, Paparis E, Coiffard LJ (May 2007). "Study of the photostability of 18 sunscreens in creams by measuring the SPF in vitro". Journal of Pharmaceutical and Biomedical Analysis. 44 (1): 270–273. doi:10.1016/j.jpba.2007.01.052. PMID 17367977.