FKBP9

Protein-coding gene in the species Homo sapiens

FKBP9

Identifiers

Aliases

FKBP9, FKBP60, FKBP63, PPIase, FK506 binding protein 9, FKBP prolyl isomerase 9

External IDs

OMIM: 616257; MGI: 1350921; HomoloGene: 31434; GeneCards: FKBP9; OMA:FKBP9 - orthologs

Gene location (Human)

Chr.	Chromosome 7 (human)^[1]

Band	7p14.3	Start	32,957,404 bp^[1]
Band	7p14.3	End	33,006,930 bp^[1]

Gene location (Mouse)

Chr.	Chromosome 6 (mouse)^[2]

Band	6 B3\|6 27.74 cM	Start	56,809,044 bp^[2]
Band	6 B3\|6 27.74 cM	End	56,856,343 bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

stromal cell of endometrium

epithelium of colon

Achilles tendon

smooth muscle tissue

placenta

gallbladder

Descending thoracic aorta

subcutaneous adipose tissue

ascending aorta

right coronary artery

Top expressed in

vestibular sensory epithelium

vestibular membrane of cochlear duct

iris

ciliary body

utricle

calvaria

Epithelium of choroid plexus

molar

vas deferens

fossa

More reference expression data

BioGPS


More reference expression data

Gene ontology
Molecular function	calcium ion binding FK506 binding isomerase activity peptidyl-prolyl cis-trans isomerase activity metal ion binding
Cellular component	endoplasmic reticulum cytoplasm
Biological process	protein folding chaperone-mediated protein folding protein peptidyl-prolyl isomerization
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


11328


27055

Ensembl


ENSG00000122642


ENSMUSG00000029781

UniProt


O95302


Q9Z247

RefSeq (mRNA)


NM_001284341 NM_001284343 NM_007270


NM_012056

RefSeq (protein)


NP_001271270 NP_001271272 NP_009201


NP_036186

Location (UCSC)

Chr 7: 32.96 – 33.01 Mb

Chr 6: 56.81 – 56.86 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

FK506-binding protein 9 is a protein that in humans is encoded by the FKBP9 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000122642 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000029781 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Patterson CE, Gao J, Rooney AP, Davis EC (May 2002). "Genomic organization of mouse and human 65 kDa FK506-binding protein genes and evolution of the FKBP multigene family". Genomics. 79 (6): 881–9. doi:10.1006/geno.2002.6777. PMID 12036304.
^ "Entrez Gene: FKBP9 FK506 binding protein 9, 63 kDa".

Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Zhang H, Li XJ, Martin DB, Aebersold R (2003). "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry". Nat. Biotechnol. 21 (6): 660–6. doi:10.1038/nbt827. PMID 12754519. S2CID 581283.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Shadidy M, Caubit X, Olsen R, et al. (1999). "Biochemical analysis of mouse FKBP60, a novel member of the FKPB family". Biochim. Biophys. Acta. 1446 (3): 295–307. doi:10.1016/s0167-4781(99)00080-9. PMID 10524204.

Isomerases: geometric (EC 5.2)

5.2.1

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)