DZIP1

Protein-coding gene in the species Homo sapiens


DZIP1
Identifiers
AliasesDZIP1, DZIP, DZIPt1, DAZ interacting zinc finger protein 1, MVP3, SPGF47
External IDsOMIM: 608671; MGI: 1914311; HomoloGene: 45708; GeneCards: DZIP1; OMA:DZIP1 - orthologs
Gene location (Human)
Chromosome 13 (human)
Chr.Chromosome 13 (human)[1]
Chromosome 13 (human)
Genomic location for DZIP1
Genomic location for DZIP1
Band13q32.1Start95,578,202 bp[1]
End95,644,706 bp[1]
Gene location (Mouse)
Chromosome 14 (mouse)
Chr.Chromosome 14 (mouse)[2]
Chromosome 14 (mouse)
Genomic location for DZIP1
Genomic location for DZIP1
Band14|14 E4Start118,875,520 bp[2]
End118,925,460 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • sperm

  • left testis

  • Achilles tendon

  • right testis

  • ventricular zone

  • caput epididymis

  • right frontal lobe

  • secondary oocyte

  • stromal cell of endometrium

  • cerebellar hemisphere
Top expressed in
  • dorsomedial hypothalamic nucleus

  • lateral hypothalamus

  • spermatid

  • paraventricular nucleus of hypothalamus

  • superior colliculus

  • ventral tegmental area

  • genital tubercle

  • dorsal tegmental nucleus

  • medial vestibular nucleus

  • central gray substance of midbrain
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • protein binding
  • metal ion binding
  • nucleic acid binding
Cellular component
  • cytoplasm
  • ciliary basal body
  • ciliary transition fiber
  • centriole
  • cell projection
  • cilium
  • cytoskeleton
  • nucleus
  • nucleoplasm
  • microtubule organizing center
  • cytosol
  • protein-containing complex
  • centriolar satellite
Biological process
  • multicellular organism development
  • establishment of protein localization
  • germ cell development
  • smoothened signaling pathway
  • cell differentiation
  • spermatogenesis
  • cytoplasmic sequestering of protein
  • cilium assembly
  • regulation of protein binding
  • cilium organization
  • positive regulation of cilium assembly
  • protein localization to cilium
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

22873

66573

Ensembl

ENSG00000134874

ENSMUSG00000042156

UniProt

Q86YF9

Q8BMD2

RefSeq (mRNA)

NM_014934
NM_198968

NM_025943
NM_001360411
NM_001360412
NM_001360413

RefSeq (protein)

NP_055749
NP_945319

NP_080219
NP_001347340
NP_001347341
NP_001347342

Location (UCSC)Chr 13: 95.58 – 95.64 MbChr 14: 118.88 – 118.93 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Zinc finger protein DZIP1 is a protein that in humans is encoded by the DZIP1 gene.[5]


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000134874 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042156 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: DZIP1 DAZ interacting protein 1".

Further reading

  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Moore FL, Jaruzelska J, Dorfman DM, Reijo-Pera RA (2004). "Identification of a novel gene, DZIP (DAZ-interacting protein), that encodes a protein that interacts with DAZ (deleted in azoospermia) and is expressed in embryonic stem cells and germ cells". Genomics. 83 (5): 834–43. doi:10.1016/j.ygeno.2003.11.005. PMID 15081113.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Moore FL, Jaruzelska J, Fox MS, et al. (2003). "Human Pumilio-2 is expressed in embryonic stem cells and germ cells and interacts with DAZ (Deleted in AZoospermia) and DAZ-like proteins". Proc. Natl. Acad. Sci. U.S.A. 100 (2): 538–43. Bibcode:2003PNAS..100..538M. doi:10.1073/pnas.0234478100. PMC 141031. PMID 12511597.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Christian SL, McDonough J, Liu Cy CY, et al. (2002). "An evaluation of the assembly of an approximately 15-Mb region on human chromosome 13q32-q33 linked to bipolar disorder and schizophrenia". Genomics. 79 (5): 635–56. doi:10.1006/geno.2002.6765. PMID 11991713.
  • Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.


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