BAIAP2L1

Protein-coding gene in the species Homo sapiens
BAIAP2L1
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2KXC, 2LNH

Identifiers
AliasesBAIAP2L1, IRTKS, BAI1 associated protein 2 like 1, BAR/IMD domain containing adaptor protein 2 like 1
External IDsOMIM: 611877; MGI: 1914148; HomoloGene: 23123; GeneCards: BAIAP2L1; OMA:BAIAP2L1 - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for BAIAP2L1
Genomic location for BAIAP2L1
Band7q21.3-q22.1Start98,291,650 bp[1]
End98,401,090 bp[1]
Gene location (Mouse)
Chromosome 5 (mouse)
Chr.Chromosome 5 (mouse)[2]
Chromosome 5 (mouse)
Genomic location for BAIAP2L1
Genomic location for BAIAP2L1
Band5|5 G2Start144,201,336 bp[2]
End144,294,922 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • pancreatic ductal cell

  • secondary oocyte

  • tendon of biceps brachii

  • amniotic fluid

  • cartilage tissue

  • bronchial epithelial cell

  • duodenum

  • mucosa of ileum

  • mucosa of transverse colon

  • olfactory zone of nasal mucosa
Top expressed in
  • secondary oocyte

  • primary oocyte

  • zygote

  • right lung lobe

  • left colon

  • lumbar spinal ganglion

  • epithelium of stomach

  • pyloric antrum

  • mucous cell of stomach

  • otic placode
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
  • actin binding
  • proline-rich region binding
  • protein binding
  • cadherin binding involved in cell-cell adhesion
Cellular component
  • cytosol
  • plasma membrane
  • extracellular exosome
  • cytoskeleton
  • nucleoplasm
  • actin cytoskeleton
  • cytoplasm
Biological process
  • insulin receptor signaling pathway
  • regulation of actin filament polymerization
  • plasma membrane organization
  • positive regulation of actin cytoskeleton reorganization
  • positive regulation of actin filament polymerization
  • response to bacterium
  • regulation of insulin receptor signaling pathway
  • actin filament bundle assembly
  • actin crosslink formation
  • cell-cell adhesion
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

55971

66898

Ensembl

ENSG00000006453

ENSMUSG00000038859

UniProt

Q9UHR4

Q9DBJ3

RefSeq (mRNA)

NM_018842

NM_025833

RefSeq (protein)

NP_061330

NP_080109

Location (UCSC)Chr 7: 98.29 – 98.4 MbChr 5: 144.2 – 144.29 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 is a protein that in humans is encoded by the BAIAP2L1 gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000006453 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038859 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: BAIAP2L1 BAI1-associated protein 2-like 1".

Further reading

  • Millard TH, Dawson J, Machesky LM (2007). "Characterisation of IRTKS, a novel IRSp53/MIM family actin regulator with distinct filament bundling properties". J. Cell Sci. 120 (Pt 9): 1663–72. doi:10.1242/jcs.001776. PMID 17430976. S2CID 39973979.
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. doi:10.1016/j.cub.2004.07.051. PMID 15324660. S2CID 2371325.
  • Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi:10.1038/nature01782. PMID 12853948.
  • Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human Chromosome 7: DNA Sequence and Biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Hu RM, Han ZG, Song HD, et al. (2000). "Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning". Proc. Natl. Acad. Sci. U.S.A. 97 (17): 9543–8. Bibcode:2000PNAS...97.9543H. doi:10.1073/pnas.160270997. PMC 16901. PMID 10931946.
  • Sanger Centre T, Washington University Genome Sequencing Cente T (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.

External links

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  • 1spk: Solution Structure of RSGI RUH-010, an SH3 Domain from Mouse cDNA
    1spk: Solution Structure of RSGI RUH-010, an SH3 Domain from Mouse cDNA


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