ASCC2

Protein-coding gene in the species Homo sapiens
ASCC2
Available structures
PDBOrtholog search: PDBe RCSB
List of PDB id codes

2DI0

Identifiers
AliasesASCC2, ASC1p100, p100, activating signal cointegrator 1 complex subunit 2
External IDsOMIM: 614216; MGI: 1922702; HomoloGene: 41774; GeneCards: ASCC2; OMA:ASCC2 - orthologs
Gene location (Human)
Chromosome 22 (human)
Chr.Chromosome 22 (human)[1]
Chromosome 22 (human)
Genomic location for ASCC2
Genomic location for ASCC2
Band22q12.2Start29,788,609 bp[1]
End29,838,304 bp[1]
Gene location (Mouse)
Chromosome 11 (mouse)
Chr.Chromosome 11 (mouse)[2]
Chromosome 11 (mouse)
Genomic location for ASCC2
Genomic location for ASCC2
Band11|11 A1Start4,587,747 bp[2]
End4,635,699 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • blood

  • minor salivary glands

  • right lobe of thyroid gland

  • right lobe of liver

  • left lobe of thyroid gland

  • body of stomach

  • right adrenal gland

  • skin of abdomen

  • monocyte

  • anterior pituitary
Top expressed in
  • Paneth cell

  • ciliary body

  • yolk sac

  • urothelium

  • internal carotid artery

  • external carotid artery

  • cumulus cell

  • lens

  • retinal pigment epithelium

  • primitive streak
More reference expression data
BioGPS
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

84164

75452

Ensembl

ENSG00000100325

ENSMUSG00000020412

UniProt

Q9H1I8

Q91WR3

RefSeq (mRNA)

NM_001242906
NM_032204

NM_029291
NM_001376980

RefSeq (protein)
NP_001229835
NP_115580
NP_001356849
NP_001356850
NP_001356851

NP_001356852
NP_001356853
NP_001356854
NP_001356855
NP_001356856
NP_001356857
NP_001356858
NP_001356859
NP_001356860
NP_001356861
NP_001356862
NP_001356863
NP_001356864
NP_001356865
NP_001356866
NP_001356867
NP_001356868
NP_001356869
NP_001356870
NP_001356871
NP_001356872
NP_001356873
NP_001356874
NP_001356875
NP_001356876
NP_001356877
NP_001356878
NP_001356879

NP_083567
NP_001363909

Location (UCSC)Chr 22: 29.79 – 29.84 MbChr 11: 4.59 – 4.64 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Activating signal cointegrator 1 complex subunit 2 is a protein that in humans is encoded by the ASCC2 gene.[5][6][7]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100325 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020412 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Jung DJ, Sung HS, Goo YW, Lee HM, Park OK, Jung SY, Lim J, Kim HJ, Lee SK, Kim TS, Lee JW, Lee YC (2002). "Novel transcription coactivator complex containing activating signal cointegrator 1". Mol. Cell. Biol. 22 (14): 5203–11. doi:10.1128/MCB.22.14.5203-5211.2002. PMC 139772. PMID 12077347.
  6. ^ Sanger Centre, The; Washington University Genome Sequencing Cente, The (1998). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
  7. ^ "Entrez Gene: ASCC2 activating signal cointegrator 1 complex subunit 2".

External links

  • Human ASCC2 genome location and ASCC2 gene details page in the UCSC Genome Browser.
  • Overview of all the structural information available in the PDB for UniProt: Q9H1I8 (Activating signal cointegrator 1 complex subunit 2) at the PDBe-KB.

Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  • Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi:10.1038/990031. PMID 10591208.
  • Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM (2004). "Functional proteomics mapping of a human signaling pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
  • Carroll JS, Liu XS, Brodsky AS, Li W, Meyer CA, Szary AJ, Eeckhoute J, Shao W, Hestermann EV, Geistlinger TR, Fox EA, Silver PA, Brown M (2005). "Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1". Cell. 122 (1): 33–43. doi:10.1016/j.cell.2005.05.008. PMID 16009131.
  • Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923.
  • v
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  • 2di0: Solution Structure of the CUE Domain in the Human Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2)
    2di0: Solution Structure of the CUE Domain in the Human Activating Signal Cointegrator 1 Complex Subunit 2 (ASCC2)


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